Throughout our mental health journey, it’s natural to hit a plateau in progress. It may feel as if after all the therapy sessions, journaling, and self-care you’ve undergone, there’s still more that your mind may need in order to reach the psychological benefits you’re seeking.
One alternative medicine option known as microdosing, offers small doses of psychedelics to spark changes in the brain to alter the way they think and create tangible, psychological improvements.
What is Microdosing?
Microdosing refers to the practice of taking a very small, sub-perceptual dose of a psychedelic substance, such as LSD (lysergic acid diethylamide) or psilocybin mushrooms, typically on a regular schedule. The aim is to experience subtle cognitive and emotional benefits without the full-blown psychedelic effects associated with a standard or recreational dose.
Taking this subthreshold dose of psychedelics (typically within the 10 to 20 mcg range) allows one to operate within their daily lives without being restricted or slowed down by the normal effects of psychedelics or hallucinogens.
In some traditional indigenous healing communities, microdosing is often the preferred approach for individuals seeking healing, rather than macrodosing.
Microdosing vs. Macrodosing
“There is a long-standing history of different kinds of dosing of ‘master plants,’ as I call them, in traditional communities, where shamanic doses (or very high doses), were only taken by the maestro,” Maya Shetreat, MD, author of The Master Plant Experience tells xoNecole. “In fact, they would only offer a microdose to the people participating in the ceremony or to the person they're doing the healing on.”
While macrodosing might be more common among visitors of what Shetreat calls, “the global north,” the traditional method can vary among different communities, and in some cases, macrodosing may not be a part of their healing practices at all.
Due to the legality of psychedelics in most places, Dr. Shetreat shares that The Institutional Review Board (IRB) mandates that individuals taking psychedelics, even in microdoses, must be closely monitored in clinical or hospital settings, which can be “impractical” and often inconvenient as early research develops.
Unlike full-dose experiences, which are planned with preparation and integration sessions, microdosing doesn't make sense for such intensive monitoring. This is because microdosing involves taking sub-psychedelic doses that don't significantly alter one's state, and individuals usually take these doses every few days, making constant clinical supervision impractical for most people's daily lives.
Yarygin/Getty Images
The Benefits of Microdosing for Mental Health and Well-Being:
While research is still limited on the full range of benefits from microdosing, Dr. Shetreat shares that while subtle, there are “benefits with neuroplasticity,” meaning that neurons in the brain make new connections, even with microdoses over a period of time.
Additionally, microdosing has been shown to be beneficial for individuals who are not able, for any number of reasons, to experience large doses of psychedelics as they can be disorienting. “Some people are medically contraindicated due to their mental health or medications that they're taking, and are very sensitive to having really large psychedelic experiences,” she explains.
However, individuals with anxiety, depression, OCD, and also medical conditions, like chronic pain, autoimmunity, asthma, ADHD, and autism, have been shown to benefit from microdosing.
Is Microdosing the Best Option for You?
In terms of whether microdosing is a suitable option for you, clinical papers based on self-reported experiences suggest its potential benefits as being a safer and less intense approach to mental health issues.
“People tend to feel happier, lighter, more social, and more inclined to take good care of themselves like exercise and eat better,” Dr. Shetreat explains.
“They tend to avoid other altering substances like alcohol and feel less depressed; many people have gotten off of antidepressants using microdosing.” However, some may have concerns about microdosing due to its legality.
What To Expect From Your Microdosing Experience
Although the initial day of ingestion may not be the most potent day in terms of physical or mental experience, Dr. Shetreat shares that some individuals report having a particularly euphoric day following ingestion. “Many people experience benefits on the day that they take the microdose, but there are also people who describe the next day as being what we would call ‘The Best Day' where they feel a sense of euphoria,” she says.
In order to make the most of your microdosing experience, she suggests keeping an open mind, self-reflection, and clear intentions, which in turn, holds significant value in maximizing its benefits.
“Treat this experience with a master plant or psychedelic as being just as meaningful and sacred as a large experience can be,” she says, “Engaging in the meaning-making and thinking of it in a ceremonial way makes a difference. Coming in with a sense of preparation for the experience itself — during and afterward — has really great value.”
Let’s make things inbox official! Sign up for the xoNecole newsletter for daily love, wellness, career, and exclusive content delivered straight to your inbox.
Featured image by LeoPatrizi/Getty Images
RELATED
“Your circle is everything,” Reginae shares with a smile, and she’s not wrong. She’s all about creating spaces where we can come together, let our hair down, and vibe with like-minded women. “We deserve spaces to meet, uplift, and vibe with each other. BLK is making that happen,” she adds.
A New Era for Friendships—Social Mode Is Here!
Gen Z is all about building meaningful connections, whether it’s with a date or a new brunch buddy. That’s why Social Mode is such a big deal. Research shows that 65% of Gen Z values friendships just as much as romantic relationships. With BLK’s new feature, users can easily toggle between “Dating” and “Social,” opening up a world of platonic connections—no swiping right required.
Bahja Rodriguez, Reginae Carter, Breaunna Womack, Lourdes Rodriguez and Zonnique Pullins attend OMG Girlz "Make A Scene" Single Release & Video Viewing Party at Trap City Cafe on March 27, 2025 in Atlanta, Georgia
Photo by Prince Williams/WireImage
Reginae Carter Hosts the Ultimate Girls’ Night In—Powered by BLK Social Mode
What better way to show Social Mode in action than with an exclusive Girls’ Night In, hosted by Reginae? The event brought together top influencers, tastemakers, and press for a night of luxury, self-care, and real talk about love, sex, and relationships. From tarot readings to perfume-making and signature cocktails, the evening embodied the “soft life” vibe that many Black women are embracing in 2025—peaceful, intentional, and full of joy.
Guests mingled, laughed, and bonded over the importance of finding a tribe that supports you. It wasn’t just about fun (although there was plenty of that!)—it was about creating a circle of inspiring, strong women. “We need to stick together. We need to be each other’s village,” Reginae says, emphasizing the power of community over competition.
Sisterhood: The Real MVP
For Reginae, it’s all about friendship—and not just the surface-level kind. “We need friends who keep it real with us. The ones who can tell us when we’re right, when we’re wrong, and when we need to calm down,” she says. As someone who navigates the spotlight, she’s got the best of both worlds: friends who understand the grind and those who can give her an honest, grounded perspective.
Her advice for building strong, intentional friendships? “Be confident in yourself and know your worth,” she explains. “Also, hurt people hurt people, so make sure you’re coming from a good place when you’re building relationships. It’s not always about being nice—sometimes it’s about being real.”
Reginae couldn’t have summed it up better: “When you have the right circle, the right tribe, everything just feels easier. And that’s exactly what BLK is giving us—space to connect, laugh, and grow with each other.”
To learn more about BLK’s Social Mode, download or update the BLK app in the App Store or Google Play Store today. Who knows? You might just find your new bestie or your next brunch crew.
Let’s make things inbox official! Sign up for the xoNecole newsletter for love, wellness, career, and exclusive content delivered straight to your inbox.
Feature image by Prince Williams/WireImage